MyBioSource.com's PTF1A Antibody (C-term) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, and Western Blot. The PTF1A Antibody (C-term) was generated using PTF1, and PTF1A as the antigen and it reacts with Human.
Description
This gene encodes a protein that is a component of the
pancreas transcription factor 1 complex (PTF1) and is known to have
a role in mammalian pancreatic development. The protein plays a
role in determining whether cells allocated to the pancreatic buds
continue towards pancreatic organogenesis or revert back to
duodenal fates. The protein is thought to be involved in the
maintenance of exocrine pancreas-specific gene expression including
elastase 1 and amylase. Mutations in this gene cause cerebellar
agenesis and loss of expression is seen in ductal type pancreas
cancers